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Seneca Valley Virus 3C(pro) Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy
The oncolytic picornavirus Seneca Valley Virus (SVV-001) demonstrates anti-tumor activity in models of small cell lung cancer (SCLC), but may ultimately need to be combined with cytotoxic therapies to improve responses observed in patients. Combining SVV-001 virotherapy with a peptide prodrug activa...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466507/ https://ncbi.nlm.nih.gov/pubmed/26069962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129103 |
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