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Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus

Seneca Valley virus (SVV) is an oncolytic picornavirus with selective tropism for neuroendocrine cancers. It has shown promise as a cancer therapeutic in preclinical studies and early-phase clinical trials. Here, we have identified anthrax toxin receptor 1 (ANTXR1) as the receptor for SVV using geno...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Miles, Linde A., Burga, Laura N., Gardner, Eric E., Bostina, Mihnea, Poirier, John T., Rudin, Charles M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531414/
https://ncbi.nlm.nih.gov/pubmed/28650343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93472
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