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Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria

Chronic kidney disease (CKD) is one of the major manifestations of paroxysmal nocturnal hemoglobinuria (PNH). CKD in PNH is induced mainly by intravascular hemolysis of PNH-affected red blood cells (RBC) missing the glycosylphosphatidylinositol-anchored proteins with complement-regulatory activities...

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Bibliografiske detaljer
Udgivet i:Case Rep Hematol
Main Authors: Ninomiya, Haruhiko, Obara, Naoshi, Niiori-Onishi, Akiko, Yokoyama, Yasuhisa, Sakata-Yanagimoto, Mamiko, Hasegawa, Yuichi, Chiba, Shigeru
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466353/
https://ncbi.nlm.nih.gov/pubmed/26124968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/673195
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