Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria

Chronic kidney disease (CKD) is one of the major manifestations of paroxysmal nocturnal hemoglobinuria (PNH). CKD in PNH is induced mainly by intravascular hemolysis of PNH-affected red blood cells (RBC) missing the glycosylphosphatidylinositol-anchored proteins with complement-regulatory activities...

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Detalhes bibliográficos
Publicado no:Case Rep Hematol
Main Authors: Ninomiya, Haruhiko, Obara, Naoshi, Niiori-Onishi, Akiko, Yokoyama, Yasuhisa, Sakata-Yanagimoto, Mamiko, Hasegawa, Yuichi, Chiba, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466353/
https://ncbi.nlm.nih.gov/pubmed/26124968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/673195
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