Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as Selective Agonists of Human Formyl-Peptide Receptor 2

N-formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) that play critical roles in inflammatory reactions, and FPR-specific interactions can possibly be used to facilitate the resolution of pathological inflammatory reactions. We here report the synthesis and biological evaluation...

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Pubblicato in:Bioorg Med Chem
Autori principali: Lacivita, Enza, Schepetkin, Igor A., Stama, Madia L., Kirpotina, Liliya N., Colabufo, Nicola A., Perrone, Roberto, Khlebnikov, Andrei I., Quinn, Mark T., Leopoldo, Marcello
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466095/
https://ncbi.nlm.nih.gov/pubmed/25549897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.007
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