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Cell Autonomous and Non-autonomous Effects of Senescent Cells in the Skin

Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Demaria, Marco, Desprez, Pierre Yves, Campisi, Judith, Velarde, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466004/
https://ncbi.nlm.nih.gov/pubmed/25855157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.108
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