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Cell Autonomous and Non-autonomous Effects of Senescent Cells in the Skin

Human and mouse skin accumulate senescent cells in both the epidermis and dermis during aging. When chronically present, senescent cells are thought to enhance the age-dependent deterioration of the skin during extrinsic and intrinsic aging. However, when transiently present, senescent cells promote...

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Bibliografiske detaljer
Udgivet i:J Invest Dermatol
Main Authors: Demaria, Marco, Desprez, Pierre Yves, Campisi, Judith, Velarde, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466004/
https://ncbi.nlm.nih.gov/pubmed/25855157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.108
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