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Effect of lysine to alanine mutations on the phosphate activation and BPTES inhibition of glutaminase

The GLS1 gene encodes a mitochondrial glutaminase that is highly expressed in brain, kidney, small intestine and many transformed cells. Recent studies have identified multiple lysine residues in glutaminase that are sites of N-acetylation. Interestingly, these sites are located within either a loop...

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Bibliografiska uppgifter
I publikationen:Neurochem Int
Huvudupphovsmän: McDonald, Charles J., Acheff, Eric, Kennedy, Ryan, Taylor, Lynn, Curthoys, Norman P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465886/
https://ncbi.nlm.nih.gov/pubmed/25510640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2014.12.003
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