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Ligand regulation of a constitutively dimeric EGF receptor
Ligand-induced receptor dimerization has traditionally been viewed as the key event in transmembrane signalling by epidermal growth factor receptors (EGFRs). Here we show that the Caenorhabditis elegans EGFR orthologue LET-23 is constitutively dimeric, yet responds to its ligand LIN-3 without changi...
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| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Pub. Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4465127/ https://ncbi.nlm.nih.gov/pubmed/26060020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8380 |
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