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BAFF Blockade Prevents Anti-Drug Antibody Formation in a Mouse Model of Pompe Disease
Antibodies formed against the therapeutic protein are a life-threatening complication that arises during enzyme replacement therapy for Pompe disease (acid α-glucosidase deficiency; GAA). To provide an effective alternative to current practices, we investigated the capacity of anti-B-cell activating...
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| Publié dans: | Clin Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464966/ https://ncbi.nlm.nih.gov/pubmed/25842186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.03.022 |
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