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MERIT40 is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy
Resistance to cytotoxic chemotherapy drugs, including doxorubicin, is a significant obstacle to the effective treatment of breast cancer. Here, we have identified a mechanism by which the PI3K/Akt pathway mediates resistance to doxorubicin. In addition to inducing DNA damage, doxorubicin triggers su...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464897/ https://ncbi.nlm.nih.gov/pubmed/26027929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.004 |
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