NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer

NFAT transcription factors are key regulators of gene expression in immune cells. In addition, NFAT1‐induced genes play diverse roles in mediating the progression of various solid tumors. Here we show that NFAT1 induces the expression of the IL8 gene by binding to its promoter and leading to IL8 sec...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Kaunisto, Aura, Henry, Whitney S., Montaser-Kouhsari, Laleh, Jaminet, Shou-Ching, Oh, Eun-Yeong, Zhao, Li, Luo, Hongbo R., Beck, Andrew H., Toker, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439371/
https://ncbi.nlm.nih.gov/pubmed/25735562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2015.02.004
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