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Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis

Chronic myelogenous leukemia (CML) is a malignant disease characterized by expression of p210-BCR-ABL, the product of the Philadelphia chromosome. Survival of CML patients has been significantly improved with the introduction of tyrosine kinase inhibitors that induce long-term hematologic remissions...

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Publicat a:Leukemia
Autors principals: Thomas, EK, Cancelas, JA, Zheng, Y, Williams, DA
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464749/
https://ncbi.nlm.nih.gov/pubmed/18354486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.71
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