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Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis
Chronic myelogenous leukemia (CML) is a malignant disease characterized by expression of p210-BCR-ABL, the product of the Philadelphia chromosome. Survival of CML patients has been significantly improved with the introduction of tyrosine kinase inhibitors that induce long-term hematologic remissions...
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| Publicado no: | Leukemia |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464749/ https://ncbi.nlm.nih.gov/pubmed/18354486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.71 |
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