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Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells
BACKGROUND: Recently, we have reported the induction of apoptosis by 2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene (3-NC) in HepG2, T47D and HCT116 cells with low nano molar IC50 values. In this study, anti-proliferative effects of modified 4-aryle-4H-chromenes derivatives; 2-amino...
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Publicado en: | Cancer Cell Int |
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Autores principales: | , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4464715/ https://ncbi.nlm.nih.gov/pubmed/26074734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0204-2 |
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