Up regulation of Bax and down regulation of Bcl2 during 3-NC mediated apoptosis in human cancer cells

BACKGROUND: Recently, we have reported the induction of apoptosis by 2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene (3-NC) in HepG2, T47D and HCT116 cells with low nano molar IC50 values. In this study, anti-proliferative effects of modified 4-aryle-4H-chromenes derivatives; 2-amino...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Naseri, Mohammad Hassan, Mahdavi, Majid, Davoodi, Jamshid, Tackallou, Saeed Hesami, Goudarzvand, Mahdi, Neishabouri, Shima Hallaj
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464715/
https://ncbi.nlm.nih.gov/pubmed/26074734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0204-2
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