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Reovirus FAST Proteins Drive Pore Formation and Syncytiogenesis Using a Novel Helix-Loop-Helix Fusion-Inducing Lipid Packing Sensor

Pore formation is the most energy-demanding step during virus-induced membrane fusion, where high curvature of the fusion pore rim increases the spacing between lipid headgroups, exposing the hydrophobic interior of the membrane to water. How protein fusogens breach this thermodynamic barrier to por...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Read, Jolene, Clancy, Eileen K., Sarker, Muzaddid, de Antueno, Roberto, Langelaan, David N., Parmar, Hiren B., Shin, Kyungsoo, Rainey, Jan K., Duncan, Roy
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464655/
https://ncbi.nlm.nih.gov/pubmed/26061049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004962
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