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Molecular docking and simulation of Curcumin with Geranylgeranyl Transferase1 (GGTase1) and Farnesyl Transferase (FTase)

Protein prenylation is a posttranslational modification that is indispensable for translocation of membrane GTPases like Ras, Rho, Ras etc. Proteins of Ras family undergo farnesylation by FTase while Rho family goes through geranylgeranylation by GGTase1. There is only an infinitesimal difference in...

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Bibliografske podrobnosti
izdano v:Bioinformation
Main Authors: Subramani, Parasuraman Aiya, Narala, Venkata Ramireddy, Michael, R Dinakaran, Lomada, Dakshayani, Reddy, Madhava C
Format: Artigo
Jezik:Inglês
Izdano: Biomedical Informatics 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464541/
https://ncbi.nlm.nih.gov/pubmed/26124569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011248
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