Molecular docking and simulation of Curcumin with Geranylgeranyl Transferase1 (GGTase1) and Farnesyl Transferase (FTase)

Protein prenylation is a posttranslational modification that is indispensable for translocation of membrane GTPases like Ras, Rho, Ras etc. Proteins of Ras family undergo farnesylation by FTase while Rho family goes through geranylgeranylation by GGTase1. There is only an infinitesimal difference in...

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Gepubliceerd in:Bioinformation
Hoofdauteurs: Subramani, Parasuraman Aiya, Narala, Venkata Ramireddy, Michael, R Dinakaran, Lomada, Dakshayani, Reddy, Madhava C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Biomedical Informatics 2015
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Hypothesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464541/
https://ncbi.nlm.nih.gov/pubmed/26124569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011248
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