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Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition

Cilia regulate several developmental and homeostatic pathways that are critical to survival. Sensory cilia of photoreceptors regulate phototransduction cascade for visual processing. Mutations in the ciliary protein RPGR (retinitis pigmentosa GTPase regulator) are a prominent cause of severe blindne...

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Udgivet i:Sci Rep
Main Authors: Rao, Kollu N., Li, Linjing, Anand, Manisha, Khanna, Hemant
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463945/
https://ncbi.nlm.nih.gov/pubmed/26068394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11137
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