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Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs

Classic semiquantitative proteomic methods have shown that all organisms respond to a mild heat shock by an apparent massive accumulation of a small set of proteins, named heat-shock proteins (HSPs) and a concomitant slowing down in the synthesis of the other proteins. Yet unexplained, the increased...

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Bibliographic Details
Published in:Cell Stress Chaperones
Main Authors: Finka, Andrija, Sood, Vishal, Quadroni, Manfredo, Rios, Paolo De Los, Goloubinoff, Pierre
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463922/
https://ncbi.nlm.nih.gov/pubmed/25847399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-015-0583-2
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