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Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis
In the crowded environment of human cells, folding of nascent polypeptides and refolding of stress-unfolded proteins is error prone. Accumulation of cytotoxic misfolded and aggregated species may cause cell death, tissue loss, degenerative conformational diseases, and aging. Nevertheless, young cell...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Netherlands
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745260/ https://ncbi.nlm.nih.gov/pubmed/23430704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0413-3 |
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