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Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis

In the crowded environment of human cells, folding of nascent polypeptides and refolding of stress-unfolded proteins is error prone. Accumulation of cytotoxic misfolded and aggregated species may cause cell death, tissue loss, degenerative conformational diseases, and aging. Nevertheless, young cell...

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Bibliografske podrobnosti
Main Authors: Finka, Andrija, Goloubinoff, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745260/
https://ncbi.nlm.nih.gov/pubmed/23430704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0413-3
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