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4,4'-Diisothiocyanostilbene-2,2'-disulfonic Acid (DIDS) Ameliorates Ischemia-Hypoxia-Induced White Matter Damage in Neonatal Rats through Inhibition of the Voltage-Gated Chloride Channel ClC-2

Chronic cerebral hypoperfusion is believed to cause white matter lesions (WMLs), leading to cognitive impairment. Previous studies have shown that inflammation and apoptosis of oligodendrocytes (OLs) are involved in the pathogenesis of WMLs, but effective treatments have not been studied. In this st...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Zhao, Baixiong, Quan, Hongyu, Ma, Teng, Tian, Yanping, Cai, Qiyan, Li, Hongli
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463656/
https://ncbi.nlm.nih.gov/pubmed/25961953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160510457
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