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4,4'-Diisothiocyanostilbene-2,2'-disulfonic Acid (DIDS) Ameliorates Ischemia-Hypoxia-Induced White Matter Damage in Neonatal Rats through Inhibition of the Voltage-Gated Chloride Channel ClC-2

Chronic cerebral hypoperfusion is believed to cause white matter lesions (WMLs), leading to cognitive impairment. Previous studies have shown that inflammation and apoptosis of oligodendrocytes (OLs) are involved in the pathogenesis of WMLs, but effective treatments have not been studied. In this st...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Zhao, Baixiong, Quan, Hongyu, Ma, Teng, Tian, Yanping, Cai, Qiyan, Li, Hongli
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463656/
https://ncbi.nlm.nih.gov/pubmed/25961953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160510457
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