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Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9
Matrix metalloproteases (MMPs) MMP-2 and MMP-9 have been implicated in the physiological catabolism of Alzheimer's amyloid-β (Aβ). Conversely, their association with vascular amyloid deposits, blood-brain barrier disruption, and hemorrhagic transformations after ischemic stroke also highlights...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463451/ https://ncbi.nlm.nih.gov/pubmed/25897080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610931 |
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