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Matrix Metalloproteinase-9 (MMP-9) Is Synthesized in Neurons of the Human Hippocampus and Is Capable of Degrading the Amyloid-β Peptide (1–40)

We reported earlier that the levels of Ca(2+)-dependent metalloproteinases are increased in Alzheimer’s disease (AD) specimens, relative to control specimens. Here we show that these enzymes are forms of the matrix metalloproteinase MMP-9 (EC3.4.24.35) and are expressed in the human hippocampus. Aff...

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Опубликовано в: :J Neurosci
Главные авторы: Backstrom, Jon R., Lim, Giselle P., Cullen, Michael J., Tökés, Zoltán A.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579235/
https://ncbi.nlm.nih.gov/pubmed/8987819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-24-07910.1996
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