Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

Reversal of HIV-1 latency by small molecules is a potential cure strategy. This approach will likely require effective drug combinations to achieve high levels of latency reversal. Using resting CD4(+) T cells (rCD4s) from infected individuals, we developed an experimental and theoretical framework...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Laird, Gregory M., Bullen, C. Korin, Rosenbloom, Daniel I.S., Martin, Alyssa R., Hill, Alison L., Durand, Christine M., Siliciano, Janet D., Siliciano, Robert F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463209/
https://ncbi.nlm.nih.gov/pubmed/25822022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80142
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