Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

Reversal of HIV-1 latency by small molecules is a potential cure strategy. This approach will likely require effective drug combinations to achieve high levels of latency reversal. Using resting CD4(+) T cells (rCD4s) from infected individuals, we developed an experimental and theoretical framework...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Laird, Gregory M., Bullen, C. Korin, Rosenbloom, Daniel I.S., Martin, Alyssa R., Hill, Alison L., Durand, Christine M., Siliciano, Janet D., Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463209/
https://ncbi.nlm.nih.gov/pubmed/25822022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80142
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