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TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts
Current strategies to alter disease-associated epigenetic modifications target ubiquitously expressed epigenetic regulators. This approach does not allow specific genes to be controlled in specific cell types; therefore, tools to selectively target epigenetic modifications in the desired cell type a...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463192/ https://ncbi.nlm.nih.gov/pubmed/25866970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77321 |
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