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Mesodermal Nkx2.5 is necessary and sufficient for early second heart field development
The vertebrate heart develops from mesoderm and requires inductive signals secreted from early endoderm. During embryogenesis, Nkx2.5 acts as a key transcription factor and plays essential roles for heart formation from Drosophila to human. In mice, Nkx2.5 is expressed in the early first heart field...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461860/ https://ncbi.nlm.nih.gov/pubmed/24613616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.02.023 |
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