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Determination of HDV ribozyme N(-1) nucleobase and functional group specificity using internal competition kinetics
Biological catalysis involves interactions distant from the site of chemistry that can position the substrate for reaction. Catalysis of RNA 2′-O-transphosphorylation by the HDV ribozyme is sensitive to the identity of the N(-1) nucleotide flanking the reactive phosphoryl group. However, the interac...
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| Publicado no: | Anal Biochem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461535/ https://ncbi.nlm.nih.gov/pubmed/25937290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.04.024 |
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