Characterization of a “high” TNF-α phenotype in moderate-to-severe asthmatic children

Systemic TNF-α expression is increased in a subset of children with moderate-to-severe asthma despite aggressive corticosteroid treatment and is associated with poor asthma control. Phenotypic-directed TNF-α inhibition may be of benefit in some asthmatic children.

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Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol
Main Authors: Brown, Sheena D., Brown, Lou Ann, Stephenson, Susan, Dodds, Jennifer C., Douglas, Shaneka L., Qu, Hongyan, Fitzpatrick, Anne M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461527/
https://ncbi.nlm.nih.gov/pubmed/25725987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.08.054
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