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Hierarchical Conformational Analysis of Native Lysozyme Based on Sub-Millisecond Molecular Dynamics Simulations

Hierarchical organization of free energy landscape (FEL) for native globular proteins has been widely accepted by the biophysics community. However, FEL of native proteins is usually projected onto one or a few dimensions. Here we generated collectively 0.2 milli-second molecular dynamics simulation...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Wang, Kai, Long, Shiyang, Tian, Pu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461368/
https://ncbi.nlm.nih.gov/pubmed/26057625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129846
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