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Hierarchical Conformational Analysis of Native Lysozyme Based on Sub-Millisecond Molecular Dynamics Simulations

Hierarchical organization of free energy landscape (FEL) for native globular proteins has been widely accepted by the biophysics community. However, FEL of native proteins is usually projected onto one or a few dimensions. Here we generated collectively 0.2 milli-second molecular dynamics simulation...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Kai, Long, Shiyang, Tian, Pu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461368/
https://ncbi.nlm.nih.gov/pubmed/26057625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129846
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