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Purification of the Cucumber Necrosis Virus Replicase from Yeast Cells: Role of Coexpressed Viral RNA in Stimulation of Replicase Activity

Purified recombinant viral replicases are useful for studying the mechanism of viral RNA replication in vitro. In this work, we obtained a highly active template-dependent replicase complex for Cucumber necrosis tombusvirus (CNV), which is a plus-stranded RNA virus, from Saccharomyces cerevisiae. Th...

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Detalhes bibliográficos
Main Authors: Panaviene, Zivile, Panavas, Tadas, Serva, Saulius, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC446104/
https://ncbi.nlm.nih.gov/pubmed/15254197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.15.8254-8263.2004
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