Proteomics Analysis of the Tombusvirus Replicase: Hsp70 Molecular Chaperone Is Associated with the Replicase and Enhances Viral RNA Replication

Plus-strand RNA virus replication occurs via the assembly of viral replicase complexes involving multiple viral and host proteins. To identify host proteins present in the cucumber necrosis tombusvirus (CNV) replicase, we affinity purified functional viral replicase complexes from yeast. Mass spectr...

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Bibliographic Details
Main Authors: Serva, Saulius, Nagy, Peter D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395393/
https://ncbi.nlm.nih.gov/pubmed/16474124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2162-2169.2006
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