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AAV-mediated miRNA Delivery and Therapeutics

MicroRNAs are 20-24 nt long, single-stranded RNAs that repress gene expression. Dysregulation of miRNA expression is associated with many human diseases. Modulating the level of endogenous miRNA alters gene profiling and can achieve therapeutic benefits. Here, we reviewed currently used methods of a...

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Detalhes bibliográficos
Publicado no:Semin Liver Dis
Main Authors: Xie, Jun, Burt, Daniel Robert, Gao, Guangping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460833/
https://ncbi.nlm.nih.gov/pubmed/25632938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0034-1397352
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