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Crosstalk of the Insulin-Like Growth Factor Receptor with the Wnt Signaling Pathway in Breast Cancer

The insulin-like growth factor system has long been considered a pathway that promotes cell proliferation, survival, and transformation, and is thus a promoter of tumorigenesis. However, recent failure of clinical trials for IGF-1R inhibitors reveals the need for a better understanding of how this p...

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Bibliografische gegevens
Gepubliceerd in:Front Endocrinol (Lausanne)
Hoofdauteurs: Rota, Lauren M., Wood, Teresa L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460810/
https://ncbi.nlm.nih.gov/pubmed/26106366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2015.00092
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