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Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis

P2X receptors constitute a seven-member family (P2X1-7) of extracellular ATP-gated cation channels of widespread expression. Because P2X receptors have been implicated in neurological, inflammatory and cardiovascular diseases, they constitute promising drug targets. Since the first P2X cDNA sequence...

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Detalhes bibliográficos
Publicado no:Curr Med Chem
Main Authors: Hausmann, Ralf, Kless, Achim, Schmalzing, Günther
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460280/
https://ncbi.nlm.nih.gov/pubmed/25439586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867322666141128163215
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