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Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels
Store-operated calcium entry (SOCE) regulates a wide variety of essential cellular functions. SOCE is mediated by STIM1 and STIM2, which sense depletion of ER Ca(2+) stores and activate Orai channels in the plasma membrane. Although the amplitude and dynamics of SOCE are considered important determi...
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| Publié dans: | J Cell Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460148/ https://ncbi.nlm.nih.gov/pubmed/26033257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201412060 |
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