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Structural features of STIM and Orai underlying store-operated calcium entry
Store-operated calcium entry (SOCE) through Orai channels is triggered by receptor-stimulated depletion of Ca(2+) from the ER. Orai1 is unique in terms of its activation mechanism, biophysical properties, and structure, and its precise regulation is essential for human health. Recent studies have be...
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| Publié dans: | Curr Opin Cell Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462238/ https://ncbi.nlm.nih.gov/pubmed/30716649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2018.12.012 |
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