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Structural features of STIM and Orai underlying store-operated calcium entry

Store-operated calcium entry (SOCE) through Orai channels is triggered by receptor-stimulated depletion of Ca(2+) from the ER. Orai1 is unique in terms of its activation mechanism, biophysical properties, and structure, and its precise regulation is essential for human health. Recent studies have be...

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Vydáno v:Curr Opin Cell Biol
Hlavní autoři: Qiu, Ruoyi, Lewis, Richard S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462238/
https://ncbi.nlm.nih.gov/pubmed/30716649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2018.12.012
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