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STIM1 gates the store-operated calcium channel ORAI1 in vitro

Store-operated Ca(2+) entry through the plasma membrane Ca(2+) release–activated Ca(2+) (CRAC) channel in mammalian T cells and mast cells depends on the sensor protein stromal interaction molecule 1 (STIM1) and the channel subunit ORAI1. To study STIM1-ORAI1 signaling in vitro, we have expressed hu...

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Autors principals: Zhou, Yubin, Meraner, Paul, Kwon, Hyoung T, Machnes, Danya, Oh-hora, Masatsugu, Zimmer, Jochen, Huang, Yun, Stura, Antonio, Rao, Anjana, Hogan, Patrick G
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902271/
https://ncbi.nlm.nih.gov/pubmed/20037597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1724
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