Initial activation of STIM1, the regulator of store-operated calcium entry

Physiological Ca(2+) signalling in T lymphocytes and other cells depends on the STIM-ORAI pathway of store-operated Ca(2+) entry. STIM1 and STIM2 are Ca(2+) sensors located in the endoplasmic reticulum (ER) membrane, with ER-luminal domains that monitor cellular Ca(2+) stores and cytoplasmic domains...

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Autores principales: Zhou, Yubin, Srinivasan, Prasanna, Razavi, Shiva, Seymour, Sam, Meraner, Paul, Gudlur, Aparna, Stathopulos, Peter B, Ikura, Mitsuhiko, Rao, Anjana, Hogan, Patrick G
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784406/
https://ncbi.nlm.nih.gov/pubmed/23851458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2625
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