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Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

Stromal interaction molecules (STIM)s function as endoplasmic reticulum calcium (Ca(2+)) sensors that differentially regulate plasma membrane Ca(2+) release activated Ca(2+) channels in various cells. To probe the structural basis for the functional differences between STIM1 and STIM2 we engineered...

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Detalhes bibliográficos
Main Authors: Zheng, Le, Stathopulos, Peter B., Schindl, Rainer, Li, Guang-Yao, Romanin, Christoph, Ikura, Mitsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029719/
https://ncbi.nlm.nih.gov/pubmed/21217057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015125108
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