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Synthesis and structure-activity relationships of novel cationic lipids with anti-inflammatory and antimicrobial activities

Certain membrane-active cationic steroids are known to also possess both anti-inflammatory and antimicrobial properties. This combined functionality is particularly relevant for potential therapies of infections associated with elevated tissue damage, e.g. cystic fibrosis airway disease, a condition...

詳細記述

保存先:
書誌詳細
出版年:Bioorg Med Chem Lett
主要な著者: Myint, Melissa, Bucki, Robert, Janmey, Paul A., Diamond, Scott L.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459899/
https://ncbi.nlm.nih.gov/pubmed/26004577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.104
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