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Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models

Gentamicin may cause acute kidney injury. The pathogenesis of gentamicin nephrotoxicity is unclear. Autophagy is a highly conserved physiological process involved in removing damaged or aged biological macromolecules and organelles from the cytoplasm. The role of autophagy in the pathogenesis of gen...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Cui, Jing, Bai, Xue-Yuan, Sun, Xuefeng, Cai, Guangyan, Hong, Quan, Ding, Rui, Chen, Xiangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459224/
https://ncbi.nlm.nih.gov/pubmed/26052900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11256
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