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Toll-like receptor 4 contributes to vascular remodelling and endothelial dysfunction in angiotensin II-induced hypertension

BACKGROUND AND PURPOSE: Toll-like receptor 4 (TLR4) signalling contributes to inflammatory cardiovascular diseases, but its role in hypertension and the associated vascular damage is not known. We investigated whether TLR4 activation contributed to angiotensin II (AngII)-induced hypertension and the...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Hernanz, R, Martínez-Revelles, S, Palacios, R, Martín, A, Cachofeiro, V, Aguado, A, García-Redondo, L, Barrús, M T, de Batista, P R, Briones, A M, Salaices, M, Alonso, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459031/
https://ncbi.nlm.nih.gov/pubmed/25712370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13117
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