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Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells

BACKGROUND AND PURPOSE: Leptin, an adipokine synthesized by the placenta during pregnancy, has been proposed for the management of preterm labour (PTL), as it is able to prevent in vitro uterine contractility and remodelling associated with labour onset. Another common feature of labour onset is the...

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Bibliografiska uppgifter
I publikationen:Br J Pharmacol
Huvudupphovsmän: Barrichon, Marina, Hadi, Tarik, Wendremaire, Maeva, Ptasinski, Clémentine, Seigneuric, Renaud, Marcion, Guillaume, Delignette, Marc, Marchet, Jacques, Dumas, Monique, Sagot, Paul, Bardou, Marc, Garrido, Carmen, Lirussi, Frédéric
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459017/
https://ncbi.nlm.nih.gov/pubmed/25653112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13100
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