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Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells
BACKGROUND AND PURPOSE: Leptin, an adipokine synthesized by the placenta during pregnancy, has been proposed for the management of preterm labour (PTL), as it is able to prevent in vitro uterine contractility and remodelling associated with labour onset. Another common feature of labour onset is the...
Sparad:
I publikationen: | Br J Pharmacol |
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Huvudupphovsmän: | , , , , , , , , , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
BlackWell Publishing Ltd
2015
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459017/ https://ncbi.nlm.nih.gov/pubmed/25653112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13100 |
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