Dose-dependent biphasic leptin-induced proliferation is caused by non-specific IL-6/NF-κB pathway activation in human myometrial cells

BACKGROUND AND PURPOSE: Leptin, an adipokine synthesized by the placenta during pregnancy, has been proposed for the management of preterm labour (PTL), as it is able to prevent in vitro uterine contractility and remodelling associated with labour onset. Another common feature of labour onset is the...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Barrichon, Marina, Hadi, Tarik, Wendremaire, Maeva, Ptasinski, Clémentine, Seigneuric, Renaud, Marcion, Guillaume, Delignette, Marc, Marchet, Jacques, Dumas, Monique, Sagot, Paul, Bardou, Marc, Garrido, Carmen, Lirussi, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459017/
https://ncbi.nlm.nih.gov/pubmed/25653112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13100
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