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Secretome Analysis Identifies Novel Signal Peptide Peptidase-Like 3 (SPPL3) Substrates and Reveals a Role of SPPL3 in Multiple Golgi Glycosylation Pathways

Signal peptide peptidase-like 3 (SPPL3) is a Golgi-resident intramembrane-cleaving protease that is highly conserved among multicellular eukaryotes pointing to pivotal physiological functions in the Golgi network which are only beginning to emerge. Recently, SPPL3 was shown to control protein N-glyc...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Kuhn, Peer-Hendrik, Voss, Matthias, Haug-Kröper, Martina, Schröder, Bernd, Schepers, Ute, Bräse, Stefan, Haass, Christian, Lichtenthaler, Stefan F., Fluhrer, Regina
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458722/
https://ncbi.nlm.nih.gov/pubmed/25827571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.048298
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